its not completely impossible but it would be alot of work and not a high priority for now
alright than what Sotha92 said: add more enemies or even better, give the enemies more randomly choosen abilities the farther you get (like the kind a monster gets from evolving). I would love that varying factor and it would make the game much harder the farther you got. Maybe also let enemies fuse and temper their items like 1 temper every loop or smt?