At least in the start and tutorial screen your game is not responsive for higher resolutions: 
I wasn’t able to craft something, should it just happen after I collected the ingredients? At least this is what I understood from the tutorial.
Regarding the controls, I would use the left mouse button to engage, the constant switch between keyboard and mouse is annoying (on my keyboard, I can’t reach space with the left hand, probably my bad ;-)).
Besides these, the game looks really good. Gameplay-wise, I would start much smaller, the number of recipes, ordered items and ingredients is just overwhelming at the beginning.