I'm not sure. It's a keyboard that I have to hold Fn to access the F1-F12 keys (otherwise they do like volume and stuff) but even doing that doesn't seem to work. Using F1-F12 for game controls is a little bit unusual anyway; usually they're reserved for application commands (e.g. F1 for help, F11 for fullscreen), so I think other people might appreciate it having another key binding as well.