Very funny set-up and I didn't encounter any bugs. For spelling the weed killer does say that it "poisions" enemies instead of poisons. The game was fun although it would be better with abilities to shake things up rather than just consumable items. I also found that the healing potion's numbers were way too low. Often times I would take more damage from their turn than I would heal up, making it better to keep swinging than to spend any time healing. Also the dandelions apply poison so often that it doesn't make sense to use an antidote until you've killed them which isn't necessarily bad but essentially takes any decision making out of the equation.
The pixel art is pretty solid and fits the silly vibe of the game. The biggest feedback I would give on that side is that Ms. Wilson herself is a bit out of place because everything is fairly isometric/top-down but she looks like she is drawn from a side-on perspective. Making her head bigger and her body smaller would help to make her look like she is being viewed from the same angle as the rest of them. But otherwise, I think the rest fit with each other.