i used https://ezgif.com/sprite-cutter this tool to cut the spritesheet into individual images so i can put them on 3d cubes.. or quads lol .. i dont plan to alter the images or the colors or any pixels just to use this to make it easier to work with and then ill use SuperCombiner to make it back into a texture atlas lol ... actually could just use blender and set the UVs to match to the sprite sheet too hmm.. whatever...
i guess technically the best thing would be to seperate the sheet into optimal 8x ~ images for each category (geometry, props, monsters, items, ui) ... but . shrug.. .. ~ (by scene set of each level)