Ok, update. I literally started implementing it, and I was about halfway through the dialogue when I decided to change my mind for one reason that I did not think of earlier.
A theme that I have in this game is having the futas flip misogyny on men. Some aspects are obviously exaggerated (at least for the modern-day context) and to be honest it's not like I'm making this game as a statement for feminism. I'm not sure how feminists would feel about the way I portray it, anyway, since the discrimination is being fetishized.
But I digress. When I started rewriting the script for a female protagonist, it felt too real in the sense that it seemed genuinely hurtful in a way that it doesn't for men.
I don't know if this makes sense and I am sorry to disappoint. Maybe this could change in the future. But, for the time being, I think this is going to remain exclusively a futa-on-male game.