Here's a basic guide for the Nightclub if people are confused:
If a room has a lightning bolt, it means the power failed. Use the drone on the box next to the door and do the minigame to fix it. This happens often if you clean a room that doesn't require cleaning, so don't just mash the clean buttons constantly.
If a room as a green lock symbol, check the 4 trash cans on the lower level. There's a racoon messing about in one of them. Use the robot to walk up and kick the trash can to make her leave.
If one of your girls heart meter maxes out, she will eventually come to relieve her stress on you. This costs you time (Which means customers) and usually ends up making all the rest of the girls horny. It also makes them unavailable to customers. This can end up causing a domino effect of not being able to get anything done as they constantly come in to use you. Use the ! buttons on either side of the desk to close the doors if one of them is horny. They will smack the door and reset. Usually. Basically just keep closing the doors every time you come back from the camras until they're all back to normal.
NEVER UNDER ANY CIRCUMSTANCES PUT ARI IN THE TOP RIGHT (Diamond) ROOM. EVER.
General tip: If you get clowns, they are guaranteed to make a mess of the room. I usually try to stuff them into the upper rooms as you can see those symbols from your desk and it's much easier to tell which one needs to be cleaned that way.
Oh, and if you have the time for it, you can click the little white circle rabbit when viewing a room camera to change the angle/position. You can also place a girl on the stage in the main room if you feel like it, but this doesn't do anything useful, gameplay wise.
Here's a tip for remembering the door layout on the ground floor, since you can't see them. Heart is on the right, Clubs is on the left, so: Hear-ight, Cl-eft. That's how I do it, anyway.
Spoilers for last day ahead:
When you 'win' the final day and the 'overtime' starts, you can completely ignore the girls and the rooms. Focus entirely on defusing, all of the girls lust meters will stop rising after this point. The faster a bomb is flashing, the closer it is to detonation, so focus those first.