I just looked into this again and it turns out it's a bit harder to fix than I thought. However, the game should work fine in Safari! Try it and let me know if you have any issues. Thanks!
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Thanks for looking into it. After having problems with a couple other games, I posted about it and there's a little discussion going. I think we've figured out that it's a Chrome update issue, and not something you'll be able to fix for macOS users until Chrome fixes it (or unless you're willing to remove all shaders from your game, which is what I just did for an old game that was broken by this).
I haven't figured out why everything is broken in Safari, as that seems to be a separate issue. I don't know if it's a recent change, as I haven't used itch.io on Safari before now, when I started having issues with Chrome. My understanding is that Safari is less compatible in general. For your game, it runs but at an unplayable 4fps in Safari. Many others are entirely broken, which they may always have been due to the macOS WebGL2 incompatibilities.
It is often difficult to know whether something is a problem in our hands, or on the game engine to fix, or the browser, the operating system, the universe itself...
Graphific found a fix and I was able to play this game running it in the current chrome dev build! Which means a future chrome update should fix the issue for regular chrome users on mac.
I got a score of 200! Very lovely game with such nice movement, art, and sound. Took a few tries to understand the movement but once I did I got into a nice flow. Glad we all figured it out so that I could play :)