It could be that you're not in range. If you look at the top of the screen, you should see a prompt that tells you to interact and it will turn gold when you're in range and grey otherwise. The character or object will also have a white outline. As mentioned in the notes, some animations cause the visuals to move away from their colliders, which is an unfortunate bug that can't be fixed as submissions are closed. So the colliders might not be where the character physically appears, but should still function if you search for it. The easiest one to check is the Goddess since she has a massive hitbox directly over the fountain. Could you try that and confirm?
Also, does Left-Mouse Button do anything for you?