I actually somehow did manage to use the larger powerball but the quest didn't update which confused me. Also am I mistaken or is there a limit to how many of the more powerful ones I can shoot? It felt like I could spam shoot like ~5 of them and then I had to wait for them to reload which is not a bad mechanic but I couldn't see any indicator of that being the case.
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Ooh, for performance I used object pool instead of initiating new object each time. It is somewhat acting like interval mechanic, if you shoot too much, you use up all the powerball objects in the pool, and each shoot has 3 seconds lifetime to reset, so if you shoot too fast you eventually trigger something like an ability cooldown which was not intended but I also think it is cool lol :D