This is really creative, love seeing all the "illness" you've came up with. Models are really cutely made, and I love the BGM made for this.
The instruction in the guidebook is a little vague. Based on the icons, I didn't know what I needed to do after chopping/grinding the ingredients. That image you had in your itch.io page description clarified it for me, maybe you can add that into the game itself, either that or show a 3rd icon to put into the pillmaker after chopping/grinding.
Please dive further into the inspection part of this game if you ever decide to expand this. It is such a cool idea to be able to rotate your patients around and inspect them of the symptoms of their illnesses before giving them a correct cure. As of now, the illnesses are a little too obvious to identify.
I really like this entry, it has so much potential for something amazing! Thanks for making this!