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I give up. I have been messing around whit this for days and I must be doing something wrong.

How do you do alchemy? Do you put in the mushrooms one by one and brew each of them or you put in all three at the time in the correct order and brew them all at once?

Do you have to do anything else after you brew what ever you needed to do or you just need to exit the basement and see something changed.

Also... anyone knows what to do whit the thirsty tree and where to find a key for the chest under the mushroom cluster. The fragile keys don't seem to work.

Alchemy requires you to put in the required mushrooms all at once and then brew it. No need to put them in the exact order.

You use the item that appears in your inventory after brewing a potion to get it's effect.

If you are trying to get True Sight, you eat the mushrooms rather than brew them.

The PC will only attempt the thirsty tree's request if you were caught by a Malice. That quest only becomes relevant once that happens.

That chest is related to the tree that wants a Lilyth mushroom. The Fragile Keys do not work. This is a hint and not the full solution.

Just adding to what VocalRhapsody said in reference to the thirsty tree: Both getting infected with Malice, and triggering thirsty tree's request are linked to the same time of day. More details on that in your journal, but Do Not go infect yourself unless you already have thirsty tree's 'tip'.