Great visuals! Loved that you tried to innovate on the match 3 concept, you may need to reward the player for throwing more potions at a time (maybe a scoring combo system)
You could rethink the controls, currently the right hand moves from mouse to keyboard, maybe only assigning a number per color, pressing the number adds the potion to the queue? This could make it smoother to play.
Also, lower the music volume and add a lose panel / retry button, but this is polishing. Loved playing it!