Hey Ben - download the updated zip for v1.0.8, which contains these updates as well as an important change that I hope will help newbies understand things better: the shop icon for each weapon will instead be the DNA letter.
Keep at it - think of the time before your first win as just the tutorial. Once you've got lots of Research and you start to really get the hang of things, it'll feel like a breeze (for example: you'll almost always be able to afford something after wave 1 after maxing out the Biomass-related researches).
Once you get further, you'll realize that "depths" are ascensions, too.