1. Creepy Crawlies - 2 attempts, after killing queen nothing happens and quest giver don't whant to speak with me.

2.Missing Person - This mission send me to ruins without stairs 

3.Leprosy  - After infection im able to move only few squares and totally stuck after. If i use any skill or make shoot anywhere i can move few steps and stuck again.  Somehow i come to the doctor and healed this desease (and replace leg for the better one) and now can move properly.

4.Stolen Blade - 3 attempts, mission mark send me to kindred Hideout, try to check all villages on map, no marks for thief (don't know if Thief must be marked somehow)

5.Vampire desease can be applyed twice 

This damage seems a little too much ... or it's intended?

Those three quests are unfortunately known to be broken under various circumstances. I'm working on a quest system rewrite at the moment, which should hopefully solve the bugs people have been reporting. 

Leprosy must have some kind of exception happening on every turn refresh. I'll take a look, though I think I know the culprit. 

999 damage? Definitely not intended. I thought I scaled back explosive damage in the last update. Hm. I'll take another look at that code.