Cheating is the wrong word. But you wouldn't get away with it in the ratings. :P
Can't you just reset the render target back to 64x64 after resizing the window?
Seems like i can't change resolution of the window independently from back buffer. But i can create RenderTarget2D with size 64x64, then upscale main back buffer and draw my rendertarget scaled. This should allow any subpixels!
Yeah, that works! Subpixels are no more, thanks for an idea!