>"For many the Default Route  (w/o cheating!)  can be very difficult, & if you're unlucky,  impossible."

Eh?  There are some less intuitive elements since it's an alpha work in progress, but the game is easily beatable without much effort. 
Just set yourself and all your girls to fishing.  You can prioritize slaves with a high wits factor, but it's not necessary.  Similarly, fishing rods will help but don't stress out over them.  The strategy is to maximize the # of slaves fishing as quickly as possible, and there are a lot of ways to improve your efficiency along the way but the biggest is upgrading the mansion to hold more people.  I go 4/5 beds for the first week to establish a decent buffer before upgrading the mansion, and will then wait until after the day 14 loan payment to upgrade the mansion a 2nd time.  When you reach the point where mansion rooms requires iron wood to upgrade, that's the hard signal to move girls out of the mansion into the forest to gather exotic materials.  The big difference at this point is that (pick) axes are more important for gathering high end materials like magic/iron wood and mithril, than rods are for fishing.  You will want your labor camp slaves equipped, and you will want to eventually craft them solid mithril work implements.  After you've gotten the hang of the game's meta, you'll be able to swiftly align efficiency bonuses to quickly jump straight to mining and selling mithril to short circuit production.  Using this method, it's possible to accrue enough wealth to pay off the full cost of the loan, completely upgrade the mansion, and fully kit out all your slaves with good gear.  Prostitution is a red herring, since each girl needs to have her sex stats trained up personally, you won't be able to scale production as quickly; the harlot class tree provides methods for increasing obedience in the work camps.  

When it comes to getting rep, beyond doing all the quests they put on the notice board, you should note that quest generation is kinda out of the way if you dismiss/ignore the tutorial.  At the guild, you can push the upgrade button to bring up a menu for increasing # and quality of hirelings. Pressing "Quest Generation" brings up yet another popup where you can change the difficulty level of quests the guild assigns.  You will want to raise the difficulty of the quests as you go to maximize reputation gains.

>-Characters & classes  (esp if non-human)

To minmax your PC along the lines described above, you'll want to start with PHYS1, WIT5, CHA4, SEX1, and MAG4.  Caster and Soul Eater class give +1 MAG, and Dominator gives WIT+1.  You can spend money and wood at the slave market to upgrade your PHYS and SEX factors; you will want to do this prior to doing the lich hunting and myr's sister quests so you can get their events.  The initial slave assigned by the guild should be built similarly.  Race isn't super important, but I like having the init girl be a dark elf for the magic attack boost and access to druid.  For the first few days, you'll want to use your date to study together.  This will quickly raise wits for both characters, improving fishing efficiency and granting access to higher tier spells.  The aoe attacks employed by casters are very OP, and the demoness boss with her high MDEF is inserted as a counter to that play style, but you can just pummel her with your staff.  Though by that point you really should have at least one decently equipped fighter-type standing in the front row.  Right click her to bring up the weaknesses.

>-Did you do any quests that pay -0- gold?   Do any servants Quests?  [have yet 2 meet anybody who got 500 pts there]

Even if the quest doesn't offer gold, items and rep rep are still valuable. I always get the 500 with all four guilds for the necklace, but the random quest generation does frequently push servants to be the last one.  With lucky quest gen, I've gotten 500 with all four by day 28 (before the loan payment for that day), but more frequently hitting it around day 42-48. If you keep an open bed slot, you can buy slaves for servant guild requests.  Training up the various slaves Amelia requests can be a pain, so I just do the item requests and simple factor quality requests.  Unfortunately, in the first few weeks of the game, slaves for servant guild requests will provide less gold compensation than the cost of the slave requested, but that rep is valuable itself.  Sex toy is great for maintaining obedience in work camps, and breeder has obvious utility.  

>-Did you buy weapons or make your own?   [fighting doesn't pay much but weapons R *EXPENSIVE*!]    [eg,  staffs can cost 1k gold or more]

You will want to do both.  In the first 2 weeks, you won't have access to a blacksmith so it's your only option.  You will want yourself and your 2nd caster to both have decent staves.  It's less important that your fighter be equipped at that point.  They exist mostly to stand between you and the goblins while you cast spells.  Longer term, you will craft your own weapons for use and buy weapons to disassemble; the latter being a reliable way to obtain rare ingredients like obsidian, adamantine, and the like.  Outside of the main questline, you enter dungeons to fulfill guild requests or get rare materials which are otherwise ungatherable.  Most notably mythic leather and adamantine.

>Ya she's cute 2 look at,    but PTP   (Practicality Take Precedence)  

Honestly, the game really isn't that tight.  I always grab Daisy, and I pick all her classes based on aesthetic principles.  Right now she has Pet, Maid, Bard, Cook and Head Girl, next will probably be alchemist, and it doesn't matter that I haven't upgraded any of her factors yet.  Though in terms of absolute practicality, as I said earlier: the fighter on the front row is mostly there to stand between you and the goblins and doesn't need gear or training to fulfill that purpose.  Stacking bard and the other utility classes can provide practicality in the mid game, and by the end game you should have slaves on every node making mats so abundant you can afford to fully upgrade each individual slave.

>(Milford good source:   Grain/WOOD, IRON----& usually closest good source to home. [Inc Travel affects Obed etc] )

Milford is trash.  You can just buy grain, wood, and iron in the city, and the travel affecting obedience is just a one time transition tax.  Once the slaves arrive, they can use their obedience abilities on each other so they all stay in line.  This is as easy as including 2 with the pet class, but having someone with maid or watchdog on site is also handy.  If you need extra wood send your slaves to the next town over where they can get silk, which isn't sold in the quantities that you'll need for making magic cloth.  Otherwise send them into the forest or the caves for higher end materials.  If you have access to the smithy, then you're ready to send people mithril mining.  Worker, Foreman, and Trainer classes go a long way to improving efficiency on mithril and ancient bone.

Honestly I just sell materials if I don't have enough from the quests. I've so far started with a magic user in the first run, and a worker in the second run. Fairy race for both runs (didn't realize at the time that other races also had hidden classes). In the first one I got some of the most cursed quests, for example my mage guild would only offer me aphrodisiac quests, my fighters guild only wanted me to full clear dungeons with the occasional slay x amount of bandits, my servants guild just spam asked me for permanent workers instead of the 3 day lease variety, and my worker guild wanted increasingly drastic amounts of food. In that run I actually had to go through I think 3? debts before getting the points needed. Didn't help that I didn't really know what I was doing either. 2nd run I only had to do 1 payment and got some fairly blessed early quests, it was overall significantly easier.

A few pieces of advise: Do not hire poor growth workers to keep, only to fill quests at best. Always aim for at least good on the ones you are going to keep and always check all the guilds as well for recruits. Avoid trying to clear out dungeons before you are ready, it can be incredibly expensive time wise if you end up dying. Make sure no workers are idle, always have them chopping wood, mining stone or iron, or at the very least getting food. Even if you don't use the materials they harvest, you can sell them to make up whatever deficit you have come debt time. Also use the "date" function every 24 hours to fill loyalty, or train workers for quests. 

Oh and as for upgrades, only do tailoring and smithing until you get the debt taken care of. Otherwise you starve yourself for materials and waste a lot of time farming them. Doing it this way in my 2nd run got me through the debt phase on like day 21ish I believe.

Edit: Forgot to mention how I got through Dungeon / Slaying quests. Either your main character or 1st servant need to be some form of combat class obviously. I usually side with the fighters guild first so I can get the sword and armor, then go archer class on the 1st servant to  get wind flurry which hits 2 enemies at 0 cost, you can use it with any weapon. Then I'd send my fairy master in with the 1st servant cause he gets access to the once per day fairy heal ability that heals 50% hp. That will easily get you through any slay quests, for the Clear Dungeon ones, you need either your Master to be a healer or have a 2nd servant thats some form of combat class. If you need any extra classes, make sure you use the 'Date' option every chance you can as well as clicking 2 people for some bedroom fun, you can also get exp through intercourse in this after all.

Edit 2: So I initially thought prostitution was a red herring job early, but then I tried a 'challenge' run more or less where I ONLY use prostitution to get out of the debt, Master was a Rabbit, first servant was a Fox. And....on day 3 I had the 1k I needed for the first debt. I imagine by the time I reach the deadline, the 14th day, I'll already have enough for the 3rd loan payment. The only downside to this is that there are very few guild tasks my mansion full of prostitutes can do. And ofc my first 4 tasks were all of the "go slay some wolves" variety. So its probably still gonna take me a while to move past the debt phase, but I doubt I will ever have much trouble paying.

Ok, so I've been playing the game for a while now, and got a pretty solid grasp on things and mechanics, but not to the point of minmaxing yet.

I've tried to run things 2 ways mostly. I've made it to day 14 getting 500 rep with all 4 guilds by changing the quests on day 7 to medium difficulty and running bandit dungeons and farming some slaves from those, either for gold or personnel. My start is always the same:

1st slave: Dark Elf. Apprentice (Druid-Caster-Necromancer). You build your Master to be your nuker early on, and since you have to worry about training high wits ASAP, I'd recommend buying a slave that can benefit from wits early on aswell, either a second magic user or a worker, to spend the first day building up your wits with that slave.

Side with fighters. Don't sell anything you can use yet, we're not in a rush. Unless it is for an improvement, or an extremely good slave.

2nd slave: Seraph (Fighter-Valkyrie-Knight) or another high health race. I like Seraphs for the sole fact that you can get holy lance by day 4 to 5 by doing physical training, and that allows you to snipe those bandit assasins and make your day7+ runs much smoother.

3rd slave: Worker/2nd Nuker, whatever is available with high wits. This slave will have to be your lockpicker/fisher early on, so make sure you spend that first day training your wits with it.

The first couple of days are just goblin runs. Demolish stone shrines, ignore others, lockpick with your 3rd slave, and just keep using your social skills building up obedience/loyalty. Once you're confident your team can take on bandit dens, you go and start farming slaves. I usually get there by day 3 or 4, depending on the first golbin runs and the gear i have with me.

What's important to have in mind is that demolishing shrines gives you a lot of stones/obsidian early on that can make a difference by the time you get to hour 23 and want to go to the shop and trade for food/gear before the reset happens at 0hs.

Make sure you rush your rooms to expand towards making a second team to run in parallel with your main team, either by splitting the first team or starting one from scratch with a good tank. With good medium armor you can get away with a single slave frontlining and healing after combat. But things need to die for your lone frontie to stay alive through the entirety of the combat.

Use your hours wisely. You'll mostly be using them to travel to your dungeons, don't rush things.

Keep in mind always that you'll need to train every day with a slave. At the moment, there's only one interaction available per day and getting wits+charm  maxed on your master should always be a priority, so that by day 7 you can make the most out of the medium difficulty quests you'll get.

There are no hard quests, just some that take longer. If an item requested is not in the market, you can always look for it elsewhere.

Slaves come and go, so long as it's not one from your main team, they can be replaced, and even those in the main team can too.

You can also spend an extra couple of days grinding on a single slave to meet the requirements for a quest, it's fine so long as you remember to multitask and not rush to the next day to complete the training. If you don't rush your hours, you'll get to day 14 with 500+ rep on at least 3 guilds AND 1k+ gold.

If you would like me to expand on this I'd be happy to document a run and post it somewhere.

Ok so I was already well underway with a run, but I'm gonna start one from scratch and document it for you, and please do mind that there might be some oversights to certain aspects I'd assume you're familiar with.

   Master - Dark Elf (+5 MATK) - Apprentice (+10 Wits)

PHY 1 - WIT 4 - CHA 4 - SEX 1 - MAG 5 (You could argue that 5th point can go to either CHA or WIT but I prefer starting with high magic affinity right away)

Likes fish, hates meat. Sex trait: Curious.

   1st Slave - Fighters guild - Seraph (140% Health, 10% light resist, and the most important thing, Valkyrie as class upgrade) - Fighter (+5 Physics, +15 Health, + 5 Speed)

GRO 5 - PHY 5 - WIT 5 - MAG 4 (Rest with no additional points but here's the gist: the first slave is usually my frontline and ends up with high wits/physics thanks to some training and working, so it also ends up being my upgrade/crafter)

Likes fish, hates meat. Sex trait: Curious.

   Day 1:

Grab 4 quests: Workers want 14 bones, Servants want a female with at least average timid, Fighters want 8 goblins defeated, Mages want 2 aphrodisiacs. Market has 2 aphrodisiacs on day 1 so we complete one quest. The slave market has a female with average timid factor but it's over 300 so not worth it. Buy 2 aphro, complete the quest, that's +272 gold (-200 spent +472 reward). I buy mana and health crystals from the shop. Change quest difficulty to medium (because I might forget later)

There's no staff on the shop, but there's a slave that caught my eye.

   2nd Slave - Slave Market - Halfkin Tanuki (115% health, +5 Wits) - Fighter, Rogue (Crit Chance +3 , Speed +10)

GRO 2 - PHY 3 - MAG 3 - WIT 3 - CHA 2 - SEX 3 - TAM 4 - TMD 3 (Basically, this slave will be a second frontline)

Loves fish.

I put extra rations on everyone and luxury room on my first slave. Use praise and sedate once on each, then date with my Seraph to train wits. Sex with them too to get a little bit of experience, and check my dungeons. Goblin cave 3 hours away, so we head there. Armor on 1st slave, sword on 2nd, nothing on PC.

My 2nd slave hits around 30 with ordinary attack, while PC and 1st hit for around 15-20.

Inside the dungeon I completed the Fighter quest, and got Druid with my PC before the boss fight, so I healed up my team, finished the run and farmed the leather for a couple of hours. The leather is important for the stables upgrade. Sell some obsidian I got from demolishing the stones, and bought some food. Saved 200 gold, and ended the day with my team resting.

   Day 2:

   3rd Slave: Daisy

I always get Daisy ASAP so I can start training charm on her and my PC, that way I can make the most out of the training sessions. And she's an extra body for dungeons, since we're only healing with druid heals with no staff atm.

Team: PC Dark Elf Apprentice, Druid - 1st slave Seraph Figher, Watchdog - 2nd slave Halfkin Tanuki Figher, Rogue, Watchdog - 3rd slave Daisy

With 4 members I can easily tackle more goblin dungeons until I farm enough gear to move on towards bandit dens and better gear.

Daisy can be useful in dungeons after getting Harlot, since she can distract enemies and bosses, which is sort of a help, and she's the one that demolishes shrines from now on, that way if she gets cursed, she's not that important and therefore the debuffs don't have a big impact in the rest of the team, who are the damage dealers. Basically, she's the cursed bitch.

I bought 3 goblin runs on day 2, completed the Workers quest, bought/farmed some gear and got back to the mansion to rest for a couple of hours. I lucked out on getting an adamantine spear from the shop, which I completely forgot to check, and a steel staff. So now my team is ready for bandit dens.

Consume all the social skills you have, they're useful ways to boost obedience, and your slaves also can help you with that.

   Day 3:

Now the team is set to run bandit dens and farm wood and slaves to get the Servants quest done.

Team: PC Dark Elf Apprentice, Druid, Caster, Necromancer (yes, I got to 75 wits with the last chest on my 3rd goblin run) - 1st slave Seraph Fighter, Watchdog, Trainer, Worker - 2nd slave Halfkin Tanuki Fighter, Rogue, Watchdog, Trainer - Daisy Harlot, Natural Pet.

At this point, the 2 fronties are geared enough for the dens, and we do enough damage to clear the first one without casualties, and get the last bit we need to expand our rooms.

After running 2 dens, we completed the last quest for the Servants with one of the slaves at the end.

So before finishing the day, I go to the shop and trade some leftover gear for food and queue up the mansion upgrade for rooms. At the moment I only have 4 people, and haven't kept any extra slaves, so I'll run another den after doing 0hs training.

   Day 4:

Team: Same as the previous day, with my Seraph now a Valkyrie and Daisy a Dancer.

After finishing expanding the rooms, the objective here is to get the best possible gear/slaves we can from runs, because now we have 2 great nukers which are our Necromancer with Decay, and our Valk with Holy Lance and Swipe.

I'll update when I get the chance to continue with this save.

TBH, never had too much of a problem.  I always go smarty-pants (because I'm a huge nerd who wants to be a wizzard! instead of something manly) and do a crapton of fishing.  I don't waste money on tools (they pay for themselves eventually, but I stop worrying about money eventually) for the most part and only worry about getting the easy quests done (and hoping they're easy enough).  

I "cheat" in that I only advance the plot when I feel ready.  Need me to run fast and find the criminal?  Too bad, I'm scavenging 12 bandit dens and making better armor first.  He'll still be "about to escape" 4 weeks from now when I finish my Ancient Medium Armor and scavenge enough ancient wood to make a super-staff.  

I *do* have to chase the suspension of loan payments, but making the first 2 payments is actually quite easy.  Payment 3 or 4 is when I have to have gotten enough rep to advance the plot to the election cycle.  Once that happens I'm coasting.  

depending how many risks you are willing to take.

dark elf or fairy for the magic attack stat + apprentice class for master > custom slave - side with workers guild go with a human  + worker class + high phys with tmd and tam, stack the equipment on them travel to a village with wood cotton food , sit there farming wood and cotton, usually check slavers guild, buy a few other slaves with worker class or blank if not avaliable and spread them out accross resouces. that's pretty much an easy foundation to work off since buy about the 2nd or 3rd day can be upgrading the mansion to have room for another 5 slaves. daisy is a safe pick up usually go farmer class and then into pure social classes afterwards

Other way i will do it is worry about the 1st payment and the 2nd payment so about 4k total and just rush faction quest on medium or hard quests, make sure to get meat soups for the healer class and just rely on fish and wood for resources where possible can be through becoming mayor quest before end of 3 payment, from there smooth sailing. i do recommend going either archer or rouge on the master, siding with either mages or fighter guild and having a peon scholar for the custom slave for the heals. just recommend getting peons with the figher, rouge, or scholar class, and just rush a caster and healer, druids are a plus same with fairy because of the innate healing skill per day.

with the start of the civil war quests usually spend a bit of time building up gear and stats since no pressure of time constraints. dragonkin and seraphs are worth while if you see them at the exotic slave trader. And start moving resource production into the mansion.

usually have both questlines done by about day 60 give or take.

usual build for fairy - apprentice > druid > rouge > archer > scholar > caster > theif > necromancer

if fairy or mage just leave them on fishing there's no real need for them to be taken off of fishing.

social slaves just rush dancer and watchdog all you really need and have a class on them for gathering materials get more use out of them. one dancer per resource village - leather collars and maid outfits go along way with making it less micromanagement.

human slaves are prefered with worker outfit, respective tools and class for the job they're doing due to racial bonus.

master stat's i tend to do a 3 split on all and boost up physics charm and sexual just to bypass the lich fight, get the scene with aire and have options for the final bit with anastasia

worth taking zephyra to elven capital for the interaction there to save sacrificing someone .

daisy quest is usually done to the outfit for the bonus's and completed at end of game. 

shop items - usually will buy up axes and sicles when i see them, weapon wise ancient/obsidian and draconic are worth buying just a minor financial setback but saves making gear in the long run.  armour wise i usually tend to just use what's rewarded in quests and loot in dungeons.

there's no real incentive to stress over getting the classes in the faction shops they're not worth while or worring about they're just an after thought don't need them to beat game. blood mage and healer is a nice combo with mass heal and using health to restore manor.

with just melee and archer slaves i will usually stick scholar on them for a back up healer to keep the main one's alive.

Female char, witch quest: 

it saves time to start with a male elf as your first slave, or hire one in the first weeks.

If you face the witch without having an Elf in your party, go back to Aliron and buy or hire any male elf. The witch isn't choosy; I just sold that elf when she was done with him.

I've played to the Mines quest a few times now, here's my tips:

Character Creation:

You get to create a master and your first slave, then get a Bunny girl in the first night.

Creating the char it helps to put 5 into Charm. 

I'd recommend setting some stats to 5. 

Now for Classes:

As you gain XP you'll unlock classes. These provide additional skills, and increase a stat. It helps to think about each person's role:

- Paladin (e.g.  Scholar (single heal) with 4 physics, then get Warrior, Worker for the Physics and Harvesting bonus, and either Healer (unlocked from the church's food quest) or make him an Elf and get Druid. (Healer group-heals and rezzes. Druid has a very useful AoE attack and group heal). Many magic staffs also have good melee; switch him to a stronger melee weapons if you have more than one other caster.

- My Seductress/Whore classes get Bard immediately, then Maid Pet Geisha and usually Farming. I find it useful to upgrade them to 2 Phys and give them hunter for the double attack.

- Pure mage: Very useful to have two casters with group heals, as group heals have a cooldown and sometimes the enemies do focus someone in your party.

My first successful playthrough was with a Paladin main (moderate in everything) and a Paladin with Magic and Phys maxed; I then understood how the upgrade system works: Each upgrade requires a rarer type of wood. It pays to have some stats at 5 from the outset, and just upgrade your level-1 stats to 2 using 100 gold and 10 wood after day 14. (You'll need to save up gold until then).

2nd playthrough was harder: Rogue/Fighter/Worker main with a Mage as a partner. Having two mages who can AoE and have different damage types and mass heals really helps in the harder fights.

3rd playthrough: Whore/Succubus main with a Paladin partner. I hired a fourth char on day one to make up for her weaker combat skills, and got lucky with guild tasks so I could also get Daisy. My whore main now has the Mines quest, did some medium bandit hideouts, gave birth, has all the charm and sex skills I could find, and still doesn't make a lot from prostitution :D

Current playthrough just started, "easy mode" with two male mages. my plan is to upgrade the bedroom and molest Daisy a lot. :D

Strategy from day one:

Create Main, go to town, talk to a guild and create first slave. I recommend siding with Mages for a good Staff, which makes your caster a bit imba from the start.

Check noticeboard. 

Possible tasks:

- craft (energy shard, collar, ears ...) - ignore until you have the room built. You may get lucky and get a task for3 Energy shards, these sometimes drop in Goblin Caves. 

- farm (meat wood stone etc) - these are great for day one, maybe except Bone.

- single fight (wolves are quite easy, bandits a bit harder. Accept but save for day 2 or 3)

- kill a number of goblins or bandits. Accept if it says Goblins (Bandits is a bit tougher but manageable).

- Complete a dungeon. These are quite easy, accept and save for day 3.

- need slave for 3 days (usually needs a combination of gender and class. Easy to do only that slave will be gone for three days.) 

- need slave (you can buy one and train them up, but usually at a loss I think. Like if it needs a male harlot with sexuals 20, you'll have to hire someone, do a dungeon or two with them (or have them read a valuable XP scroll) until they can learn Harlot, date and train them, then have them work as a whore until the stats are up. And then turn them in at a loss. I'll skip these next time.)

Go home, date your first slave, click Travels, find a resource you need (if you don't have quests, just go farm foods). 

At midnight or 1 am day 2, go to Aliron, check town, get Daisy. Set her to fishing, return your workers.

When everyone's back, date Daisy, praise both. Doubleclick your Scholar if you have one and make sure he has the staff equipped. 

Click Crafting, you should have enough resources to start crafting meat soup.

Go to Aliron, "Buy Dungeon", buy a Goblin Cave. 

I now just buy or hire a fourth character as soon as possible. Enter the goblin cave, Advance. If you have a Mage first slave, and they have a Staff, they can one-shot most goblins. So everyone except your mage with the staff focuses on one enemy. Your caster heals anyone whose HP are under 30, otherwise shoot the strongest enemy with fireball. You other characters all focus on the same enemy, preferably one that's already damaged. Use Magic to heal between fights. Don't use Energy shards if you only have a few, sometimes the guild wants 3 of them. 

Do not hire a fifth character yet. Your mansion can house 5 slaves max by default, you want one slot available for when you win a bandit cave or find a random slave in a dungeon. (Can just sell them, but not if you have 5 people already.)

After a fight or three, you'll be out of mana for heals. Go back to Mansion, hit Travels, go farm something useful. And/or set your casters to cook, have someone fish. If you're just a few coins short of something you want to buy, set Daisy to prostitution. When your mana is mostly replenished, do some more of the goblin cave. 

Getting Thief for your main character is useful for levelling up wits.

Buy weapons in town, even a club helps.

The cycle for me is:

- go to goblin cave until worried about mana

- go back and cook, or Travel and farm for food (occasionally wood) until mana is back up

- Always farm everything at the end of a dungeon (after the boss you get 1 locked chest, and some resources to harvest)

Your characters will become stronger with each round of these. You'll be quite weak in week 1 but should aim to have 4 people, everyone with  a weapon,  and grind goblin caves.

Random tips:

Characters may become pregnant if you forget to turn on Aphrodisiacs. (Double-click the char, click "food and details) in the bottom left. Two of my playthroughs my MC had an unplanned pregnancy, so uh ... :D

If you find a Pyramid:

If the description is something metal ... light ... Moon, it wants food. 

If the description says "sizeable hole", it wants a stone.

If the description says wood female, it wants cloth.

Gild tasks refresh each week. Check on day 6 and day 13 (I think) to make sure you've handed in any completed quests, and maybe cancel impossible ones you've accepted, in order to free that slot for a new guild quest.

For quests that I can't do or don't want to do, assignment quest being a good example, I take the quest and then forfeit it. This removes the quest so it isn't still around the next week..

I have done a Ancient Jungle quest before Day 21, I ran away a lot. Took two excursions to complete. I also do lot of dungeons (not nearly as many as some) thus I have some looted gear and lots of classes. The new random buffs on dungeon opponents can make some fights very difficult. Bard and shaman classes have become more useful.

OK, here we go:

MC: Nereid Hunter. 4 PHY, 4 CHR 5 SEX.  Sex trait: desired.  Likes fish hates whatever.

Day 1: Side with Workers and recruit: Orc Worker, PEON(this is important). 5 GRO, 5 PHY, 4 WIT, 4 CHR, 2 SEX. Sex trait: curious. Likes Fish hates whatever.  Date Orc and train PHY then sex Orc and try to maximize Orc orgasms. Use social skills to up obedience.  Set MC to fish then send Orc to the closest place that has wood, equip workers outfit and axe and set orc to gather rough wood.  Advance time until there is just enough time to bring the orc home then check the shop and buy enough rough wood to make 30 total.  It's no big deal if you have to wait a day to buy the wood but we want to start the tailor on day 3.  You'll also want to secure 5 cloth and 10 health crystals so check the shop daily until you have them. Accept any guild quests and finish any that can be easily finished with shop purchases. Bring the Orc home.

Day 2:  Same as Day one except gather/buy stone until you have 25 then immediately switch MC to upgrading and start tailor.  Remember to use all social skills on Orc including lust relief for xp.

Day 3-14:  Start as normal but send Orc to nearest iron wood site.  They will be gathering iron wood without returning until you have 15.  Once you have 15 iron wood bring orc home to finish upgrading then build a bow using iron wood for both parts then some bandages. At your first level take attendant then archer for your second.  Remember to date sex and social every day you can(you will probably miss a day while gathering iron wood).  You should be done around day 8 at which point you are ready to start solo clearing dungeons with your orc. Finish any combat quests first(remember to use lust relief option 4 now and equip that bow!) then start spamming bandit dens.  After the first dungeon run you should be able to get fighter, berserker, and thief.  You get a free slave at the end of each bandit  dungeon which you will sell unless they are a human with average or better growth either no class or one or more of the following: worker, harlot, watch dog or trainer.  Harlot is optional, really only for the reward with sex skill, but you are looking to recruit 2 humans and get the other 3 skills + foreman eventually on them.  You can use your orc to power level them and MC to build their stats with dates. Gather wood, stone, and iron from the ends of dungeons until you can make a lvl 1 forge then upgrade using your MC. Move MC to fishing whenever they aren't crafting or upgrading.  When you have your production team ready to go send them to a location with mithril and ancient bones and have them each gather one of those. Use watchdog skills to keep obeddiance up and discipline from trainer every day.  Harlots can use reward with sex as available to increase xp gain.

From here on out the game should be pretty easy.  Earthshatter from berserker will demolish  low level dungeons.  Attendant will allow you to heal without using an action as long as you have health crystals and top off with bandages between fights.  I can't stress the importance of attendant enough, the action economy means you don't have to stop killing to heal and bandages scale with your hp rather than matk.  The income from dungeons should more than pay off the bank even if you never touch the main quest and the ability to produce high quality tools from mithril and ancient bones should kick your economy into gear.